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Most synthetic cannabinoids are agonists on the cannabinoid receptors. They have been designed to be similar to THC,[nine] the organic cannabinoid with the strongest binding affinity on the CB1 receptor, and that is linked to the psychoactive consequences or "high" of cannabis.[ten] These synthetic analogs usually have greater binding affinity and greater potency to the CB1 receptors.
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Some early synthetic cannabinoids had been also employed clinically. Nabilone, a primary technology synthetic THC analog, is utilised as an antiemetic to combat vomiting and nausea considering the fact that 1981.
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It can be lawful in states where cannabis just isn't simply because its subatomic structure is analogous to that of banned narcotics. This also indicates that it's a significantly bigger effect on the brain than THC.
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